Nutrient intake in early childhood and developmental outcomes in later life
The presentations covered topics on the nutritional intake and developmental outcomes and the importance of optimizing nutrition in early life.
Hot Topics - Medical Advances In The NICU
Discussing the medical advances in Neonatology in respiratory and neurodevelopment, late preterm outcomes, and the role of nutrition.
Necrotising Enterocolitis and the Preterm Microbiome
Necrotising enterocolitis (NEC) is a devastating inflammatory condition of the gut that primarily affects preterm infants. Whilst the aetiology varies from case to case, recent data show that the onset of NEC is closely associated with the pattern of gut microbiota, especially in the few days prior to NEC onset. Recent studies suggest Human Milk Oligosaccharides (HMOs) may be a key component of breast milk associated with reductions in NEC.
Early Nutrition Preterm Infants
Mechanisms that early nutrition impacts later health including metabolic programing, brain development, gut microbiota
Nutrition and Brain Growth in Preterm Infants
There are more than 15 million preterm infants born globally every year, yet their longer term cognitive outcomes are often below average. The reasons for lower cognitive attainment are complex but are, in part, due to inadequate nutritional status. Failure to provide recommended intakes of macronutrients appears to be a common and potentially remediable factor in brain outcomes in preterm infants on the NICU.
The Role of Oligosaccharides on the Immune System and Long-term Outcomes
The viewer should have an augmented understanding of the importance of oligosaccharides in human health.
Everyone's talking about human milk oligosaccharides
The early-life gut microbiome is important for the development of immune competence in newborn infants. Mode of delivery, perinatal antibiotic use and diet are most influential to this end. Breastfeeding is associated with lower risk of gastrointestinal and respiratory infections, and possibly lower risk of diabetes and obesity, while the effect on allergies is not so clear. This suggests that breast milk-specific components may contribute. Among them are the non-digestible human milk oligosaccharides (HMOs), the third largest solid breast milk component that varies primarily due to the maternal genotype for the Secretor and Lewis genes and stage of lactation. Other milk oligosaccharides are also relevant here.